Intra-arterial nitroprusside treatment of acute experimental vasospasm.
نویسنده
چکیده
The effect of intra-arterial sodium nitroprusside infusions on acute experimental basilar artery spasm was studied in dogs. Vasospasm produced by subarachnoid hemorrhage at normal intracranial pressure was partially relieved by nitroprusside. When given by the intra-arterial route, 15 times the recommended maximum intravenous does can be infused without significant hypotension or elevation in intracranial pressure.
منابع مشابه
Intra-Arterial Nitroprusside Treatment of Acute Experimental Vasospasm
41. Van Harreveld A, Fiflcova E: Mechanisms involved in spreading depression. J Neurobiol 4: 375-387, 1973 42. Bito LZ, Myers RE: On the physiological response of the cerebral cortex to acute stress (reversible asphyxia). J Physiol (Lond) 221: 349-370, 1972 43. Duffy TE, Nelson R, Lowry OH: Cerebral carbohydrate metabolism during acute hypoxia and recovery. J Neurochem 19: 959-977, 1972 44. Gin...
متن کاملImprovement in angiographic cerebral vasospasm after intra-arterial verapamil administration.
BACKGROUND AND PURPOSE Endovascular options for therapy for patients with vasospasm after SAH include angioplasty and intra-arterial vasodilator infusion. Preliminary studies of the effects of the calcium channel antagonist verapamil on angiographic vasospasm have yielded mixed and/or qualitative results. In this study, improvement in angiographic vasospasm after intra-arterial verapamil admini...
متن کاملDelayed Bilateral Symptomatic Vasospasm after Resection of a Skull Base Meningioma: Report on a New Case and Literature Review
Background and Importance: Symptomatic vasospasm is a well-known pathology associated with ruptured aneurysms. Nevertheless, this condition is rarely found as a result of skull base tumor removal. Case Presentation: We reported a new case of 40-year-old woman previously treated for a tuberculum and diaphragma sellae meningioma showing symptomatic vasospasm after twelve post-operative days wi...
متن کاملCORRELATION BE TWEEN ENDOTHELIAL INJURY AND CEREBRAL VASOSPASM FOLLOWING A DOUBLE SUBARACHNOID HEMORRHAGE IN THE RAT
While a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (SAH), the most consistent is endothelial damage. Since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following SAH. This experimental study investigates the correlation between end...
متن کاملCoon 1 Treatment of Mechanically-Induced Vasospasm of the Carotid Artery in a Primate Using Intra-arterial Verapamil: A Technical Case Report
Background: Despite improvements in the safety and efficacy of endovascular procedures, considerable morbidity may still be attributed to vasospasm. Vasospasm has proven amenable to pharmacological intervention such as nitrates, intravenous calcium channel blockers (CCBs), and intra-arterial papaverine, particularly in small vessels. However, few studies have focused on medium to large vessel s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Stroke
دوره 11 6 شماره
صفحات -
تاریخ انتشار 1980